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1.
Magalí Rey-Campos Beatriz Novoa Alberto Pallavicini Marco Gerdol Antonio Figueras 《International journal of molecular sciences》2021,22(6)
Mytimycins are cysteine-rich antimicrobial peptides that show antifungal properties. These peptides are part of the immune network that constitutes the defense system of the Mediterranean mussel (Mytilus galloprovincialis). The immune system of mussels has been increasingly studied in the last decade due to its great efficiency, since these molluscs, particularly resistant to adverse conditions and pathogens, are present all over the world, being considered as an invasive species. The recent sequencing of the mussel genome has greatly simplified the genetic study of some of its immune genes. In the present work, we describe a total of 106 different mytimycin variants in 16 individual mussel genomes. The 13 highly supported mytimycin clusters (A–M) identified with phylogenetic inference were found to be subject to the presence/absence variation, a widespread phenomenon in mussels. We also identified a block of conserved residues evolving under purifying selection, which may indicate the “functional core” of the mature peptide, and a conserved set of 10 invariable plus 6 accessory cysteines which constitute a plastic disulfide array. Finally, we extended the taxonomic range of distribution of mytimycins among Mytilida, identifying novel sequences in M. coruscus, M. californianus, P. viridis, L. fortunei, M. philippinarum, M. modiolus, and P. purpuratus. 相似文献
2.
气藏平均地层压力跟踪计算新方法 总被引:1,自引:0,他引:1
平均地层压力是产能评价和动态分析的基础,准确、快速获取平均地层压力对高效开发气藏意义重大。基于地层压力随时间变化的规律,分析了平均地层压力的变化规律。研究结果表明:平均地层压力等效点仅随时间发生改变,平均地层压力的下降速率等于或者近似等于井底流压的下降速率。从封闭弹性驱动气藏的物质平衡方程出发,考虑偏差系数和井底流压随平均地层压力的变化,推导建立了平均地层压力跟踪计算新方法,根据生产数据可迭代计算平均地层压力。方法验证结果显示,采气速度和采出程度共同影响模型的计算结果。应用实例表明,跟踪计算法与压力恢复试井和物质平衡法之间的相对误差均较小,满足工程计算精度要求,且跟踪计算法不需依托生产测试数据,节约了测试费用,避免了测试占产。 相似文献
3.
针对现有基于视频监控的人流量统计方案成本高、算法复杂且不利于个人隐私保护的局限性,利用毫米波雷达体积小、成本低、分辨率高的特点,提出了一种基于双时间点检测的人流量监测方法。该方法先获取人体目标散射点位置和多普勒频移信息来构成点云数据,然后根据多普勒频移正负来判断人体的运动方向,并筛选具有高多普勒频移值的点云数据以降低干扰点对聚类结果的影响;在双时间点对特定区域内人员数量进行统计,并根据双时间点之间所获取的点云数据聚类结果对所统计人员数据进行修正。实验结果表明,该方法能够用匿名的方式以较高的正确率统计人员进出。 相似文献
4.
5.
《Contact lens & anterior eye》2022,45(4):101493
PurposeThe purpose of this study was to compare sign identification distances and driving performance metrics in presbyopic participants while wearing multifocal contact lenses (MFCL) and while wearing progressive addition lens (PAL) spectacles.Methods19 presbyopic participants completed PAL spectacle assessments and contact lens fitting and follow up visits before driving assessments began. These assessments occurred in a simulator equipped with a full-sized sedan on a motion platform and a 260 degree screen. Participants completed the driving task with PAL and with MFCL. Participants followed a lead car and identified signs at various distances from the road. For the two wearing conditions, comparisons of the distance along the road at which signs were identified were made using repeated measures ANOVA. Paired t-tests were used to compare driving performance for the two conditions.ResultsThere was no statistical difference in sign identification distance between PAL and MFLC for signs 32.0 m from the road side of the road (182 ± 46 m for MFCL; 205 ± 45 m for PAL; P = 0.07) or 51.4 m from the side of the road (204 ± 43 m for MFCL; 216 ± 36 m for PAL; P = 0.3). Only signs 70.2 m from the roadside showed a significant difference (207 ± 42 m with MFCL; 232 ± 39 m with PAL; P = 0.01), All distances were greater than those required to safely stop a vehicle. There were no significant differences in the driving performance metrics between the refractive corrections.ConclusionDriving performance metrics were similar for MFCL and PAL spectacles. Sign identification distances with both eyewear types were well within the distances required for safe vehicle stopping. 相似文献
6.
研究了3种微通道板基底羟基化的方法,测量了羟基化处理后微通道板基底表面水接触角及通道端面的形貌变化,分析了各种方法中微通道板基底的亲水性和腐蚀情况。实验结果表明:氨水双氧水溶液对基体表面的亲水性能提升不大,NaOH溶液对基体有腐蚀作用,经食人鱼溶液处理的基体表面亲水性明显提高且无腐蚀作用。研究了微通道板在食人鱼溶液中的浸泡时间和浸泡温度对表面亲水性的影响。结果表明:随着浸泡温度的增加,微通道板表面水接触角先减小后增大,当温度为80℃时达到极小值,浸泡时间对微通道板表面的亲水性影响不大。最终确定了微通道板表面羟基化工艺:浸泡温度为80℃,静置时间为20~60 min。 相似文献
7.
《岩石力学与岩土工程学报(英文版)》2022,14(3):813-824
Based on the nondestructive test data of operating railway tunnels in China, this paper summarizes the basic characteristics of the complex contact behavior between the rock mass and lining structure. The contact modes are classified into dense contact, local non-contact, and loose contact. Subsequently, the corresponding mechanical model for each contact mode is developed according to its mechanical characteristics using the complex variable method. In the proposed mechanical model, a special algorithm is introduced to detect whether the local non-contact zone is re-contacted. Besides, a novel conformal mapping method is also proposed to accurately calculate the mechanical response of the concrete lining. Finally, the accuracy of the proposed method is verified by comparing it with the finite element method (FEM). Several parameter investigations are conducted to analyze the effects of different contact modes on the rock–lining interaction. The results show that: (i) the height of the local non-contact area does not have a significant effect on the contact stress distribution if no re-contact occurs; (ii) backfill grouting can reduce the local stress concentration caused by poor contact modes; and (iii) reducing the friction coefficient of the interface can lead to a more uniform distribution of internal forces in the concrete lining. 相似文献
8.
9.
A robust model-free controller for a three-phase grid-connected photovoltaic system based on ultra-local model 下载免费PDF全文
In this paper, a robust model-free controller for a grid-connected photovoltaic (PV) system is designed. The system consists of a PV generator connected to a three-phase grid by a DC/AC converter. The control objectives of the overall system are to extract maximum power from the PV source, to control reactive power exchange and to improve the quality of the current injected into the grid. The model-free control technique is based on the use of an ultra-local model instead of the dynamic model of the overall system. The local model is continuously updated based on a numerical differentiator using only the input–output behavior of the controlled system. The model-free controller consists of a classical feedback controller and a compensator for the effects of internal parameter changes and external disturbances. Simulation results illustrate the efficiency of the controller for grid-connected PV systems. 相似文献
10.
为了解决合闸过程中动、静触头接触引起的振动弹跳问题.本文建立了接触系统的二自由度运动微分方程,并利用遗传算法对交流接触器吸合过程进行优化,同时通过高速摄影实验对接触弹跳的全过程进行了观察和分析.结果表明:理论与实验结果高度一致,铁心在触头分离前发生碰撞,进一步加剧触头弹跳;铁芯弹跳再次碰撞时,触头的弹跳不受影响;在接触器运行过程中,动铁芯的运动会引起系统轻微振动;采用遗传算法优化的接触器触头弹跳时间和最大振幅均减小.研究结果为进一步控制和减小接触弹跳提供了理论依据. 相似文献